Classical formula

Da Bu Yin Wan

大补阴丸 dà bǔ yīn wán also known as Da Bu Yin Pill, Greatly Tonify Yin Pill

In skin practice, Da Bu Yin Wan is used where the picture is lichen planus, petechiae, dermatomyositis.

The pattern is emptiness with fire: night sweats, burning in the chest, palms and soles, a red dry tongue and a fine rapid pulse in someone thin. Shu Di Huang restores the Yin and Blood, Gui Ban, a heavy shell, anchors the rising Yang so the heat settles rather than merely cooling, and Huang Bo with Zhi Mu drains the deficiency fire. It suits pronounced heat on a depleted base as a pill over weeks, not excess fire.

4Herbs
4Actions
1Patterns
3Conditions
2Related
Pill (Wan)Yin-nourishing formulasHeat-clearing formulas

What Da Bu Yin Wan is for

This pill works on skin that is thin, dry and hot: skin that flushes, stings or shows fine red points because the deep Yin that should cool and moisten it has run low. It rebuilds that reserve with heavy nourishing substances and drains the fire the emptiness has let rise, so the surface settles instead of flaring.

The skin looks depleted and overheated at once. It is thin, dry and easily flushed, may sting or burn without much to see, and can show small red points where the Heat has made the fine vessels leak. The colour tends to be bright in patches rather than evenly red, and the dryness is the kind that sits deep in the tissue. Where the depletion is pronounced, the same picture sits inside a body that feels hot and restless, which is why lichen planus and dermatomyositis appear on this page.

Yin is the cooling, moistening reserve. When it is badly depleted the warming side rises unopposed, and the Heat it carries shows first where the skin is thinnest: the face, the chest, the shins. Shu Di Huang restores the Yin and Blood, Gui Ban, a heavy shell, anchors the rising Yang so the heat settles, and Huang Bo with Zhi Mu drain the deficiency fire from below. The weight of the shell is the point: it pulls the flare down rather than merely cooling the surface.

This is a formula for emptiness with fire, not for excess. Where the skin is red, swollen and weeping, or the tongue carries a thick coat, the fire is excess and this heavy, cloying pill is the wrong tool. It is also heavy on digestion, so it is taken as a pill in a course of weeks, and it is not used for cold deficiency, where there is no heat to drain.

Actions

  • Nourishes Yin strongly
  • Clears deficiency Heat
  • Drains ministerial Fire
  • Anchors rising Yang

Properties

  • Taste and temperature: Predominantly sweet and salty with a bitter note. Sweet and salty nourish Yin and anchor it, bitter clears Heat and dries.
  • Organs: Kidney, Liver, Heart
  • Channels: Kidney, Liver

The pattern behind it

The pattern is severe Kidney Yin deficiency with empty fire. The Yin is the body's cooling reserve, and when it is badly depleted the warming side rises unopposed, producing the flushing, night sweats, burning and rapid pulse. The formula rebuilds the reserve with heavy nourishing substances and clears the fire from below.


Composition

The herbs in Da Bu Yin Wan, with their role and dose.

Composition of Da Bu Yin Wan
RoleHerbDosePropertiesWhy it is there
Shu Di Huang 18 to 30 g Slightly warm, Sweet Nourishes Kidney Yin and Blood deeply, rebuilding the reserve.
King Gui Ban 18 to 30 g Cold, Salty, sweet A heavy shell that nourishes Yin and anchors the rising Yang, which distinguishes this formula from simple cooling.
Huang Bo 9 to 12 g Cold, Bitter Clears and drains the deficiency Fire in the lower body.
Zhi Mu 9 to 12 g Cold, Bitter, sweet Clears deficiency Heat while moistening, so the cooling does not dry the Yin.

Patterns it treats

Yin Deficiency with Empty Heat

Thin, dry skin that flushes, stings or shows fine red points, with heat rising from deep depletion. The Yin is low and the fire is empty, so the surface is hot and undernourished at once.

How the formula is built

Two herbs build the Yin and two clear the fire. The addition of Gui Ban is what makes this formula heavier and more anchoring than other Yin tonics: it settles the rising heat rather than merely cooling it, which is why it is used when the burning and flushing are pronounced.


Skin conditions it is used for

Where this formula appears in the skin conditions of the library.


Preparation and use

Taken as prepared pills, traditionally with lightly salted warm water, two or three times a day.

Modifications

  • If the heat is very marked, the cooling herbs are increased.
  • If the Yin depletion is severe, the nourishing group is increased.
  • If the digestion is weak, the pills are taken after food.
  • Where excess Fire is present, a clearing formula is used instead.

Timing

Taken two or three times a day with lightly salted warm water.

Duration

Four to eight weeks as a course, then reassessed, as it is a chronic Yin-nourishing formula.

Diet while taking it

Avoid drying food: alcohol, fried food and heavy spice. Moistening food supports the treatment.


Safety

Contraindications

Avoid in excess Fire, where the tongue coat is thick and the pulse forceful. Avoid in Spleen and Stomach deficiency-cold with loose stools, because the heavy and cold substances burden digestion.

Interactions

Berberine from Huang Bo can affect drug metabolism and blood sugar, so coordination with a prescriber is needed.

Pregnancy

Use with caution in pregnancy. Huang Bo is bitter and intensely cold and can be harsh on the digestion.

Breastfeeding

Use only under professional guidance.

Children

Used only with professional supervision.

Before you use it

Recorded from the classical record and rewritten in this project's own words. Educational only: not a prescription, and unexplained bruising or bleeding points need medical assessment.

General safety references

General references for herbal hepatotoxicity and herb-drug interactions; they are not specific to this formula.


Origin and history

Yi Zong Jin Jian (医宗金鉴, Golden Mirror of Medicine) by Wu Qian and colleagues, Qing dynasty, 1742, attributed to the Danxi tradition.

The formula belongs to the Danxi tradition of nourishing Yin and draining fire, and it was recorded in the Qing imperial compendium in 1742. Its distinctive use of a heavy shell to anchor the Yin reflects the idea that when the fire has risen, cooling alone is not enough and the Yin must be weighted down.


Classical record

The formula is recorded in the Qing imperial compendium as a strong treatment for Yin depletion with fire rising, using a heavy shell to anchor the Yin and bitter herbs to drain the fire.

Yi Zong Jin Jian (医宗金鉴, Golden Mirror of Medicine), Qing dynasty, 1742.


Evidence note

No controlled trial of this treatment in skin conditions was identified for this entry. What is described here rests on the classical and later materia medica record and on traditional clinical use, not on controlled trial evidence, and it is not a prediction of benefit. Where skin-specific research does exist it is linked above.

Common questions

How is it different from Zhi Bai Di Huang Wan?

Zhi Bai Di Huang Wan is milder and more balanced. Da Bu Yin Wan is heavier, with a shell that anchors the Yin, and is used when the flushing and burning are pronounced.

Why is a shell used?

Heavy substances are thought to anchor the rising Yang and settle the heat rather than merely cooling it.

Can it cause digestive upset?

Yes, the formula is heavy and cold, so it is taken as a pill and avoided where digestion is weak.

Who should not take it?

Anyone with excess Fire, a thick tongue coat and a forceful pulse, or with cold deficiency and loose stools.