Classical formula

Gui Zhi Jia Long Gu Mu Li Tang

桂枝加龙骨牡蛎汤 guì zhī jiā lóng gǔ mǔ lì tāng also known as Gui Zhi Jia Long Gu Mu Li Decoction, Cinnamon Twig plus Dragon Bone and Oyster Shell Decoction

In skin practice, Gui Zhi Jia Long Gu Mu Li Tang is used where the picture is dark skin.

The surface is not held, so sweat leaks and the spirit floats, and the same person has palpitations and broken sleep. Gui Zhi, Bai Shao, Sheng Jiang, Da Zao and Gan Cao restore the Ying and Wei relationship, while Long Gu and Mu Li, two heavy astringent shells, stop the leak and settle what is floating. It is for the chronic unstable presentation, not Heat patterns with a rapid forceful pulse or acute eruptions.

7Herbs
4Actions
1Patterns
1Conditions
2Related
DecoctionYing-Wei harmonising formulasAstringent formulas

What Gui Zhi Jia Long Gu Mu Li Tang is for

This formula is for skin that cannot hold itself. It is clammy or damp to the touch, cool, and dusky in tone, on a person who is thin and depleted. The surface leaks rather than closes, the colour is flat, and the same instability that lets sweat through is what makes the skin look unsettled. The two heavy shells are the addition that turns a surface-harmonising formula into one that astringes and anchors.

The skin reads as damp and underpowered. It is moist without being hot, cool to the touch, and often dusky or dull rather than pink. Sweat appears without exertion and dries slowly, and the surface never feels properly closed. The tissue is thin and the person looks depleted, so the clamminess is not the greasy dampness of Damp-Heat but the leak of a surface that has lost its hold. There is no redness, no heat and no eruption.

Gui Zhi, Bai Shao, Sheng Jiang, Da Zao and Gan Cao restore the relationship between the Ying and Wei levels, which is the regulation the surface has lost. Long Gu and Mu Li are heavy astringent shells: they stop the leak and settle the instability that goes with it. The base formula harmonises and the shells anchor, and that combination is what separates this from plain Gui Zhi Tang. It warms, astringes and settles at once rather than clearing or releasing anything.

It is used for the chronic unstable picture. Clammy skin with poor regulation, dusky discolouration on a depleted base, and a surface that sweats without cause all fit when there is no Heat. It is not for hot skin with a rapid forceful pulse, not for acute eruptions, and not for the greasy dampness of Damp-Heat. Persistent night sweats or palpitations need medical assessment, and the heavy mineral content means the formula is separated from other medication.

Actions

  • Harmonises the Ying and Wei levels
  • Astringes and stops spontaneous sweating
  • Settles the spirit and palpitations
  • Anchors what is floating

Properties

  • Taste and temperature: Predominantly sweet and slightly sour with a mineral quality. Sweet harmonises, sour and heavy astringe and settle.
  • Organs: Heart, Lungs, Kidney
  • Channels: Heart, Lung, Kidney

The pattern behind it

The pattern is a surface and spirit that are not held. The Ying and Wei levels are out of step, so sweat leaks, and the spirit floats, so the heart races and sleep breaks. The formula harmonises the surface and settles the spirit with heavy astringent substances.


Composition

The herbs in Gui Zhi Jia Long Gu Mu Li Tang, with their role and dose.

Composition of Gui Zhi Jia Long Gu Mu Li Tang
RoleHerbDosePropertiesWhy it is there
King Gui Zhi 9 to 12 g Warm, Pungent, sweet Warms and releases the surface, regulating the Wei Qi.
Long Gu 9 to 15 g Neutral, Sweet, astringent A heavy shell that settles the spirit and astringes the sweat.
Mu Li Ke 9 to 15 g Slightly cold, Salty, astringent A shell that anchors what is floating and astringes, working with Long Gu.
Bai Shao 9 to 12 g Slightly cold, Bitter, sour Nourishes Ying and astringes, balancing the releasing herb.
Sheng Jiang 9 g Slightly warm, Pungent Warms the middle and helps harmonise the surface.
Envoy Da Zao 4 to 6 dates Warm, Sweet Nourishes the middle and the Ying level.
Gan Cao 6 g Neutral, Sweet Harmonises the formula and supports the middle.

Patterns it treats

Ying and Wei Disharmony

Clammy, cool, dusky skin that never feels properly closed, on a thin and depleted person, with sweat that appears without exertion. The surface has lost its hold rather than being hot or inflamed. The formula harmonises the surface, and the two shells astringe and anchor it.

How the formula is built

The base harmonising formula restores the Ying and Wei relationship, and the two shells add what it cannot: they astringe the leaking surface and settle the floating spirit. That is why it is used when the disharmony has produced instability.


Skin conditions it is used for

Where this formula appears in the skin conditions of the library.


Preparation and use

Decocted in water and taken warm, in two divided doses.

Modifications

  • If the sweating is marked, the astringent shells are increased.
  • If the spirit is very unsettled, settling herbs are added.
  • If Cold is present, warming herbs are added.
  • If Heat is present, cooling herbs are added.

Timing

Taken warm in two divided doses.

Duration

Two to four weeks, reassessed.

Diet while taking it

Warm light food; avoid stimulating drinks and heavy night meals.


Safety

Contraindications

Avoid in Heat patterns with a rapid forceful pulse. Use care in Dampness. Persistent palpitations or night sweats need medical assessment.

Interactions

The mineral content can affect absorption of some medicines, so it should be separated from other medication. Gan Cao may interact with diuretics, digoxin and corticosteroids.

Pregnancy

Generally considered compatible with pregnancy when appropriately prescribed, though professional guidance is appropriate.

Breastfeeding

Considered acceptable under professional guidance.

Children

Used in children with reduced dose for sweating and restlessness.

Before you use it

Recorded from the classical record and rewritten in this project's own words. Educational only: not a prescription, and persistent palpitations or night sweats need medical assessment.

General safety references

General references for herbal hepatotoxicity and herb-drug interactions; they are not specific to this formula.


Origin and history

Jin Gui Yao Lue (金匮要略, Synopsis of Prescriptions of the Golden Chamber) by Zhang Zhongjing, Eastern Han dynasty, around 220 CE.

The formula appears in the Synopsis of the Golden Chamber for the patient whose surface and spirit are both unsettled. Its two heavy shells are the addition that distinguishes it from ordinary surface harmonising, and it remains a standard formula for sweating with palpitations.


Classical record

Zhang Zhongjing recorded the formula for a floating empty pulse with sweating and palpitations, harmonising the surface and settling the spirit with heavy shells.

Jin Gui Yao Lue (金匮要略, Synopsis of Prescriptions of the Golden Chamber), Zhang Zhongjing, Eastern Han dynasty.


Evidence note

No controlled trial of this treatment in skin conditions was identified for this entry. What is described here rests on the classical and later materia medica record and on traditional clinical use, not on controlled trial evidence, and it is not a prediction of benefit. Where skin-specific research does exist it is linked above.

Common questions

How is it different from Gui Zhi Tang?

It adds Long Gu and Mu Li to settle the spirit and astringe the sweat, for the unstable pattern with palpitations.

What is a floating empty pulse?

A pulse that feels superficial but has no strength beneath, indicating a surface that is not held and a depleted interior.

Can it help clammy skin?

Where the clamminess comes from a surface that is not regulating itself on a depleted base, over weeks.

Should palpitations be assessed?

Yes. Persistent palpitations, chest discomfort or breathlessness need medical assessment.