TCM pattern

Blood Deficiency with disharmony of Liver and Spleen

肝脾不和血虚 gān pí bù hé xuè xū

8Herbs
6Formulas
5Acupoints
1Conditions
5Differentials
MixedPattern of DisharmonyLiverSpleenChronic, relapsing

Understanding Blood Deficiency with disharmony of Liver and Spleen

The Liver and Spleen are described as working together: the Spleen produces Blood and the Liver stores it, and the Liver's free flow supports the Spleen's digestion. When the relationship breaks down, both functions decline together.

The Liver side shows as dizziness, blurred vision, dry eyes and emotional restraint. The Spleen side shows as fatigue, poor appetite and loose stools.

Women often notice scanty or light periods, which is the Blood deficiency showing in the menstrual cycle. The tongue is pale and thin, especially at the sides, with a thin white coat and slight dryness.

It develops from prolonged stress and frustration combined with poor or irregular eating, overwork, or blood loss.

Treatment both harmonises the two organs and nourishes Blood. Treating only the Liver leaves the Spleen deficient, and treating only the Spleen leaves the constraint in place.


Signs and symptoms

Key signs

  • Dizziness or blurred vision
  • Fatigue and weak limbs
  • Loose stools or poor appetite
  • Scanty or light-coloured periods

Also seen

  • Dry eyes
  • Irritability alongside tiredness
  • Abdominal distension
  • Poor sleep
  • Pale complexion
  • Breast distension before periods
  • A tendency to sigh

Variations

  • Alternating constipation and loose stools
  • Cramps in the limbs
  • Low mood

Worse with

  • Skipping meals or irregular eating
  • Emotional stress or worry
  • Excessive mental work or overthinking

Better with

  • Warm nourishing cooked meals
  • Regular mealtimes
  • Rest and adequate sleep

Timing

  • Digestive symptoms worsen with stress, and dizziness worsens when tired.
  • Periods are typically light and may be delayed.

Practitioner notes

  • The tongue is pale and thin, especially pale at the sides, with a thin white coat and slight dryness.
  • The pulse is fine and wiry: fine shows the Blood deficiency, wiry shows the Liver constraint.
  • The distinction from pure Liver Blood deficiency is the marked digestive weakness with loose stools.
  • The distinction from pure Spleen Qi deficiency is the Liver signs: dizziness, blurred vision and emotional constraint.

Causes

Common causes

  • Emotional stress and frustration
  • Poor diet and irregular eating
  • Overwork and excessive mental strain
  • Blood loss from menstruation, childbirth or surgery

How it develops

  • It develops when prolonged stress meets digestive weakness.
  • If untreated, the Blood deficiency deepens and the digestive symptoms become more fixed.

Diagnosis

Diagnosis rests on Blood deficiency signs together with both Liver and Spleen signs, with a fine wiry pulse.

Tongue

  • Body: Pale and thin, especially at the sides.
  • Coating: Thin white, slightly dry.
  • Note: A red tongue would indicate Heat instead.

Pulse

Fine, Wiry

Fine shows Blood deficiency; wiry shows the Liver component.

Observation

  • Pale complexion
  • A tired bearing
  • Dry eyes

Listening

  • Sighing
  • A quiet voice

Palpation

  • Abdomen: Mild fullness and tenderness along the rib margins, with a soft weak middle.
  • Channels: LR-14 and ST-36 may feel empty or tender.

Questions that separate it from look-alikes

  • How is the appetite, and are meals regular?
  • How are the periods, and how is the vision?
  • Does stress affect the digestion?
  • Any dizziness or dry eyes?

Treatment

Principles

  • Harmonise Liver and Spleen
  • Nourish Blood
  • Support digestion so Blood can be produced
  • Free the Liver Qi gently without depleting

Herbs

Formulas

  • Xiao Yao San - The reference formula for Liver-Spleen disharmony with Blood deficiency: it harmonises, frees Qi and supports the Spleen.
  • Jia Wei Xiao Yao San - Adds cooling herbs for the version with Heat signs such as irritability and a bitter taste.
  • Si Wu Tang - The Blood tonic base, used when the deficiency dominates.
  • Gui Pi Tang - For Heart and Spleen deficiency with palpitations and poor sleep.
  • Tong Xie Yao Fang - For disharmony with alternating diarrhoea and constipation from stress.
  • Bu Zhong Yi Qi Tang - For the Spleen deficiency with sinking and fatigue.

Acupoints

Personalising the plan

  • If the Liver constraint dominates, Qi-moving herbs are increased.
  • If the Blood deficiency dominates, nourishing herbs are increased.
  • If Heat is present, cooling herbs are added.
  • If diarrhoea dominates, Spleen support is increased.

Self-care

Diet

  • Warm nourishing cooked meals at regular times
  • Blood-nourishing food: dark greens, black beans, dates
  • Avoid cold, raw and greasy food
  • Eat in a calm setting rather than while stressed

Lifestyle

  • Regular meals, no skipping
  • Manage stress and express frustration
  • Rest and adequate sleep
  • Gentle exercise

Qigong and movement

  • Flowing practice that eases tension in the ribs while remaining gentle.

How it differs from look-alikes

Patterns that can be mistaken for blood deficiency with disharmony of liver and spleen, and the contrast that separates them.

Liver Blood Deficiency

The Liver side without the marked digestive weakness and loose stools.

Spleen Blood Deficiency

The Spleen side without the Liver signs of dizziness, blurred vision and emotional constraint.

Spleen Qi Deficiency

The digestive weakness without the Blood or Liver components.

Liver Qi Stagnation

Constraint with distension and irritability but without the pallor and Blood deficiency signs.

Spleen and Heart Blood Deficiency

That picture centres on palpitations and insomnia with a pale tongue; here the digestive and visual signs lead.


Where it appears

Skin conditions in which this pattern is commonly seen.


Safety and when to get help

For anything severe, sudden or spreading quickly, read when a skin problem needs urgent care.

This page describes a TCM pattern, not a diagnosis, and a pattern can accompany more than one skin condition. Get urgent medical help for a rash with fever, confusion or feeling very unwell; skin that is blistering, peeling or spreading quickly; swelling of the face, lips or throat, or difficulty breathing; or a lesion with increasing pain, warmth, red streaks or pus. For anything persistent, severe or changing, have it assessed by a clinician before treating it yourself.

Read the skin condition pages for the red flags that belong to a specific presentation.

Urgent-sign guidance is based on standard sources: NHS anaphylaxis, NHS cellulitis, NHS Stevens-Johnson syndrome, NHS melanoma.

Evidence note

No controlled trial of this treatment in skin conditions was identified for this entry. What is described here rests on the classical and later materia medica record and on traditional clinical use, not on controlled trial evidence, and it is not a prediction of benefit. Where skin-specific research does exist it is linked above.

Common questions

Why are two organs involved?

The Spleen produces Blood and the Liver stores it, and the Liver's free flow supports digestion. Strain on one affects the other, which is why the patterns appear together.

Why do the periods become scanty?

Blood deficiency reduces the substance available for the cycle, so periods become light, pale or delayed.

Why does stress affect the digestion here?

Liver constraint is said to invade the Spleen, which is why the digestive symptoms flare specifically with stress.

When should I see a doctor?

Persistent fatigue, weight loss, irregular bleeding or blood in the stool needs medical assessment.